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因其強放射性，可用航天器、高效中子源，其活度高於[[鎇|鋂]]﹣鈹與鐳﹣鈹中子源。<ref name="b1">Russell, Alan M. and Lee, Kok Loong [http://books.google.com/books?id=fIu58uZTE-gC&pg=PA470 Structure-property relations in nonferrous metals], Wiley, 2005, [//zh.wikipedia.org/wiki/Special:BookSources/9780471649526 ISBN 978-0-471-64952-6], pp. 470–471</ref>
在醫學可造<sup>213</sup>[[鉍]]，<ref name="sep">{{cite book|doi=10.1016/j.apradiso.2004.12.003|year=2005|volume=62|issue=5|pages=667–679|title=Production of actinium-225 for alpha particle mediated radioimmunotherapy|last=Bolla|first=Rose A.|web=Applied Radiation and Isotopes|pmid=15763472|last2=Malkemus|first2=D|last3=Mirzadeh|first3=S}}</ref>或作放療。然，其可累積骨肝中，留數十年。<ref>{{cite web|last1=McDevitt|first1=Michael R.|last2=Ma|first2=Dangshe|last3=Lai|first3=Lawrence T.|last4=Simon|first4=Jim|last5=Borchardt|first5=Paul|last6=Frank|first6=R. Keith|last7=Wu|first7=Karen|last8=Pellegrini|first8=Virginia|last9=Curcio|first9=Michael J.|last10=Miederer|first10=Matthias|last11=Bander|first11=Neil H.|last12=Scheinberg|first12=David A.|displayauthors=3|title=Tumor Therapy with Targeted Atomic Nanogenerators|year=2001|web=Science|volume=294|issue=5546|pages=1537–1540|doi=10.1126/science.1064126|bibcode=2001Sci...294.1537M|pmid=11711678|url=http://www.studybusiness.com/HTML/Bio/10021/10021-04-2003-BIO-04-E.pdf}}</ref><ref>{{cite web|url=http://cancerres.aacrwebs.org/content/63/16/5084.full.pdf|title=Targeted Actinium-225 in Vivo Generators for Therapy of Ovarian Cancer|author=Borchardt, Paul E. et al.|web=Cancer Research|volume=63|issue=16|pages=5084–5090|year=2003|pmid=12941838}} {{cite web|url=http://cancerres.aacrwebs.org/content/63/16/5084.full.pdf|title=Targeted Actinium-225 in Vivo Generators for Therapy of Ovarian Cancer|author=Borchardt, Paul E. et al.|web=Cancer Research|volume=63|issue=16|pages=5084–5090|year=2003|pmid=12941838}}</ref><ref>{{cite book|author=Ballangrud, A. M. ''et al.''|title=Alpha-particle emitting atomic generator (Actinium-225)-labeled trastuzumab (herceptin) targeting of breast cancer spheroids: efficacy versus HER2/neu expression|web=Clinical cancer research : an official web of the American Association for Cancer Research|volume=10|issue=13|pages=4489–97|year=2004|pmid=15240541|doi=10.1158/1078-0432.CCR-03-0800}}</ref><ref>{{cite book|author=Ballangrud, A. M. ''et al.''|title=Alpha-particle emitting atomic generator (Actinium-225)-labeled trastuzumab (herceptin) targeting of breast cancer spheroids: efficacy versus HER2/neu expression|web=Clinical cancer research : an official web of the American Association for Cancer Research|volume=10|issue=13|pages=4489–97|year=2004|pmid=15240541|doi=10.1158/1078-0432.CCR-03-0800}}</ref>
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